Bupropion
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Bupropion ( ; marketed as Wellbutrin, Zyban, Voxra, Budeprion, Prexaton, Elontril or Aplenzin; and formerly known as amfebutamone) is an atypical antidepressant and smoking cessation aid. Its chemical name is β-keto-3-chloro-N-tert-butylamphetamine, a substituted cathinone (β-ketoamphetamine), as well as substituted amphetamine. The drug therefore is a mild psychostimulant. Its primary pharmacological action is thought to be norepinephrine-dopamine reuptake inhibition. It binds selectively to the dopamine transporter, but its behavioural effects have often been attributed to its inhibition of norepinephrine reuptake. It also acts as a nicotinic acetylcholine receptor antagonist. Bupropion belongs to the chemical class of aminoketones and is similar in structure to stimulants cathinone and diethylpropion, and to phenethylamines in general. Medically, bupropion serves as a non-tricyclic antidepressant fundamentally different to most commonly prescribed antidepressants such as SSRIs.
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| Official Wellbutrin website Official Wellbutrin website www.wellbutrin-xl.com - Web |
| List of international brand names for bupropion List of international brand names for bupropion www.merck.com/mmpe/lexicomp/bupropion.html - Web |
| Wellbutrin Pharmacology, Pharmacokinetics, Studies... Wellbutrin Pharmacology, Pharmacokinetics, Studies, Metabolism – Bupropion – RxList Monographs www.rxlist.com/cgi/generic/buprop_cp.htm - Web |
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| NAMI Wellbutrin NAMI Wellbutrin www.nami.org/.../ContentDisplay.cfm&ContentID=7388 - Web |
| Bupropion article from mentalhealth.com Bupropion article from mentalhealth.com www.mentalhealth.com/drug/p30-b04.html - Web |
