Gestational diabetes
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 Effect of insulin on glucose uptake and metabolism. Insulin binds to its receptor (1) on the cell membrane which in turn starts many protein activation cascades (2). These include: translocation of Glut-4 transporter to the plasma membrane and influx of glucose (3), glycogen synthesis (4), glycolysis (5) and fatty acid synthesis (6). |
Gestational diabetes (or gestational diabetes mellitus, GDM) is a condition in which women without previously diagnosed diabetes exhibit high blood glucose levels during pregnancy (especially during third trimester). There is some question whether the condition is natural during pregnancy. Gestational diabetes is caused when the insulin receptors do not function properly. This is likely due to pregnancy related factors such as the presence of human placental lactogen that interferes with susceptible insulin receptors. This in turn causes inappropriately elevated blood sugar levels.
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| IDF Diabetes Atlas IDF Diabetes Atlas www.diabetesatlas.org - Web |
| International Diabetes Federation International Diabetes Federation www.idf.org - Web |
| World Diabetes Day World Diabetes Day www.worlddiabetesday.org - Web |
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| More information on gestational diabetes More information on gestational diabetes www.healblog.net/gestational-diabetes/ - Web |
