Rosiglitazone

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Avandia 2-mg oral tablet

Rosiglitazone is an antidiabetic drug in the thiazolidinedione class of drugs. It works as an insulin sensitizer, by binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. It is marketed by the pharmaceutical company GlaxoSmithKline (GSK) as a stand-alone drug (Avandia) and in combination with metformin (Avandamet) or with glimepiride (Avandaryl). Annual sales peaked at approximately $2.5bn in 2006, but declined after reports of adverse effects. The drug's patent expires in 2012.

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Official website Official website www.avandia.com - Web

MedlinePlus MedlinePlus www.nlm.nih.gov/medlineplus/druginfo/meds/a699023.html - Web

Medscape Medscape www.medscape.com/viewarticle/483837 - Web

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U.S. National Library of Medicine: Drug Informatio... U.S. National Library of Medicine: Drug Information Portal - Rosiglitazone druginfo.nlm.nih.gov/drugportal/dpdirect.jsp?name=Rosiglitazone - Web

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