Antibody
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 Immunofluorescence image of the eukaryotic cytoskeleton. Actin filaments are shown in red, microtubules in green, and the nuclei in blue. |
An antibody (Ab), also known as an immunoglobulin (Ig), is a large Y-shaped protein produced by B-cells that is used by the immune system to identify and neutralize foreign objects such as bacteria and viruses. The antibody recognizes a unique part of the foreign target, called an antigen. Each tip of the "Y" of an antibody contains a paratope (a structure analogous to a lock) that is specific for one particular epitope (similarly analogous to a key) on an antigen, allowing these two structures to bind together with precision. Using this binding mechanism, an antibody can tag a microbe or an infected cell for attack by other parts of the immune system, or can neutralize its target directly (for example, by blocking a part of a microbe that is essential for its invasion and survival). The production of antibodies is the main function of the humoral immune system.
- Related: Antibody mimetic, Anti-mitochondrial antibodies, Anti-nuclear antibodies, Colostrum, ELISA, Humoral immunity, Immunology, Immunosuppressive drug, Intravenous immunoglobulin, Magnetic immunoassay, Microantibody, Monoclonal antibody, Neutralizing antibody, Secondary antibodies, Single-domain antibody, Slope spectroscopy
| Mike's Immunoglobulin Structure/Function Page Mike's Immunoglobulin Structure/Function Page www.path.cam.ac.uk/~mrc7/mikeimages.html - Web |
| Antibodies as the PDB molecule of the month Antibodies as the PDB molecule of the month www.rcsb.org/.../pdb21_1.html - Web |
| Microbiology and Immunology On-line Textbook Microbiology and Immunology On-line Textbook pathmicro.med.sc.edu/mayer/IgStruct2000.htm - Web |
Gallery for «Antibody»
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| A hundred years of antibody therapy A hundred years of antibody therapy users.path.ox.ac.uk/~scobbold/tig/new1/mabth.html - Web |
| How Lymphocytes Produce Antibody How Lymphocytes Produce Antibody www.cellsalive.com/antibody.htm - Web |
| Antibody applications Antibody applications www.ii.bham.ac.uk/clinicalimmunology/CISimagelibrary/ - Web |
