Pernicious anemia

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Immunofluorescence staining pattern of gastric parietal cell antibodies on a stomach section.

Pernicious anemia (also known as Biermer's anemia, Addison's anemia, or Addison–Biermer anemia) is one of many types of the larger family of megaloblastic anemias. It is caused by loss of gastric parietal cells which are responsible, in part, for the secretion of intrinsic factor, a protein essential for subsequent absorption of vitamin B₁₂ in the ileum.

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The Pernicious Anaemia Society The Pernicious Anaemia Society www.pernicious-anaemia-society.org - Web

Parietal cell antibody Parietal cell antibody www.antibodypatterns.com/gpc.php - Web

Antibody to GPC Antibody to GPC www.ii.bham.ac.uk/clinicalimmunology/CISimagelibrary/GPC.htm - Web

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