Protein kinase
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A protein kinase is a kinase enzyme that modifies other proteins by chemically adding phosphate groups to them (phosphorylation). Phosphorylation usually results in a functional change of the target protein (substrate) by changing enzyme activity, cellular location, or association with other proteins. The human genome contains about 500 protein kinase genes and they constitute about 2% of all human genes. Protein kinases are also found in bacteria and plants. Up to 30% of all human proteins may be modified by kinase activity, and kinases are known to regulate the majority of cellular pathways, especially those involved in signal transduction.
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| The Protein Kinase Resource The Protein Kinase Resource pkr.genomics.purdue.edu/pkr/ - Web |
| Human and mouse protein kinases: classification an... Human and mouse protein kinases: classification and index www.uniprot.org/docs/pkinfam.txt - Web |
| The Kinase Knowledgebase (KKB) The Kinase Knowledgebase (KKB) www.eidogen-sertanty.com/products_kinasekb.html - Web |
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| Kinase.Com Kinase.Com kinase.com - Web |
| Kinase/TIP Kinase/TIP www.eidogen-sertanty.com/products_tip_content.html - Web |
| AurSCOPE Kinase Database AurSCOPE Kinase Database www.aureus-sciences.com/aureus/web/guest/biology-overview - Web |
| Kinasecentral: Information on Kinase inhibitors in... Kinasecentral: Information on Kinase inhibitors in development www.kinasecentral.com - Web |
| Collection of Ser/Thr/Tyr specific protein kinases... Collection of Ser/Thr/Tyr specific protein kinases and similar sequences hodgkin.mbu.iisc.ernet.in/~king/ - Web |
| KinMutBase: A registry of disease-causing mutation... KinMutBase: A registry of disease-causing mutations in protein kinase domains bioinf.uta.fi/KinMutBase/ - Web |
| Human kinome by Manning et al. Human kinome by Manning et al. www.sciencemag.org/cgi/content/abstract/298/5600/1912 - Web |
| MAP Kinase Resource MAP Kinase Resource www.mapkinases.eu - Web |
