Von Hippel–Lindau disease
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 Slit lamp photograph showing retinal detachment in Von Hippel-Lindau disease. |
Some descendants of the McCoy family (involved in the Hatfield-McCoy feud of Appalachia, USA) as well as the Elliotts have VHL. In an article appearing in the Associated Press, it has been speculated by a Vanderbilt University endocrinologist that the hostility underlying the Hatfield–McCoy feud may have been partly due to the consequences of von Hippel–Lindau disease. The article suggests that the McCoy family was predisposed to bad tempers because many of them had a pheochromocytoma, which produced excess adrenaline and a tendency toward explosive tempers. Pheochromocytomas produce surges of adrenaline which are more often perceived as panic attacks than rage attacks. Left untreated, they will cause serious cardiovascular disease, heart attack, and stroke. Only about 20% of people with VHL get pheochromocytomas.
- See also: Wikipedia
| GeneReviews/NCBI/NIH/UW entry on Von Hippel-Lindau... GeneReviews/NCBI/NIH/UW entry on Von Hippel-Lindau Syndrome www.ncbi.nlm.nih.gov/books/NBK1463/ - Web |
| The VHL Handbook The VHL Handbook www.vhl.org/handbook - Web |
| VHL Family Alliance VHL Family Alliance www.vhl.org - Web |
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| Cancer.Net: Von Hippel-Lindau Syndrome Cancer.Net: Von Hippel-Lindau Syndrome www.cancer.net/cancer-types/von-hippel-lindau-syndrome - Web |
